Molecular Traffic Jams on DNA
نویسندگان
چکیده
منابع مشابه
The impacts of molecular motor traffic jams.
M uch of a modern person’s day is spent trying to get from point A to point B. So, too, in the cell, much time and energy is expended on shuttling organelles, protein complexes, and mRNA, called “cargos,” from point A to point B. We know that vehicle traffic slows down when roads get jammed with high-volume congestion. The traffic analogy begs the question: Do cellular highways get jammed? This...
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Despite the crowdedness of the interior of cells, microtubule-based motor proteins are able to deliver cargoes rapidly and reliably throughout the cytoplasm. We hypothesize that motor proteins may be adapted to operate in crowded environments by having molecular properties that prevent them from forming traffic jams. To test this hypothesis, we reconstituted high-density traffic of purified kin...
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Molecular motors are involved in key transport processes inside actin-based cellular protrusions. The motors carry cargo proteins to the protrusion tip which participate in regulating the actin polymerization and play a key role in facilitating the growth and formation of such protrusions. It is observed that the motors accumulate at the tips of cellular protrusions and form aggregates that are...
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We study several deterministic one-dimensional traffic models. For integer positions and velocities we find the typical high and low density phases separated by a simple transition. If positions and velocities are continuous variables the model shows self-organized criticality driven by the slowest car.
متن کاملTraffic jams: dynamics and control.
This introductory paper reviews the current state-of-the-art scientific methods used for modelling, analysing and controlling the dynamics of vehicular traffic. Possible mechanisms underlying traffic jam formation and propagation are presented from a dynamical viewpoint. Stable and unstable motions are described that may give the skeleton of traffic dynamics, and the effects of driver behaviour...
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ژورنال
عنوان ژورنال: Annual Review of Biophysics
سال: 2013
ISSN: 1936-122X,1936-1238
DOI: 10.1146/annurev-biophys-083012-130304